Key study: Review of adoption, twin and family studies of schizophrenia.
Method: Review of adoption/ twin studies (1967- 76) 3 adoption studies and 5 twin studies.
Participants: 711 from adoption studies and 511 from twin studies.
Procedure: Incidences of schizophrenia analysed from various studies.
Adoption studies: adoptive parents and siblings, compared to biological parents and siblings.
Twin studies: Concordance rate for monozygotic and dizygotic twins compared.
Findings: Increased incidence of schizophrenia in adopted children with schizophrenic biological parent. Higher concordance rate for schizophrenia in monozygotic twins (58% compared to 12% with dizygotic twins)
Conclusion: Significant genetic influence- schizophrenia (but not 100%).
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